Bael aegle marmelos linn, family rutacae, is also known as bale fruit tree, is a moderate sized, slender, aromatic tree, 6. A number of chemical constituents and various therapeutic effects of a. Phytochemical analysis on leaf extract of aegle marmelos correa sonu singh, neeta singh abstract aegle marmelos is a subtropical plant which can grow up to an altitude of 1200 m from the sea level. The purpose of this research is to investigate the chemical constituents from the green fruits of aegle marmelos. Compounds 5 and 6 were also detected from the twigs. Phytochemical and pharmacological screening of in vivo anti. It grows well in the dry forests of hilly and plain areas. Chemical composition of the essential oil of the twigs and. Mazumdarfurther studies on qualitative constituents of bael aegle marmelos correa fruits grown in the sunderbans area of west bengal indian agriculturist, 46 12 2002, pp.
Aegle marmelos seeds, total phenolic contents, folinciocaiteau reagent. Phytochemical evaluation, antimicrobial activity, and. Antidiabetic activity medicinal plant aegle marmelos. The study was carried out to investigate the antiobesity effects of aegle marmelos leaves extracts and its phytochemical constituents in vitro and in vivo. Proximate analysis revealed that moisture content, ash, protein, crude fiber, carbohydrate, ph and acid value occurred in appreciable amounts in both the fruits and leaves samples. Extensive experimental and clinical studies prove that aegle marmelos possesses. Studies on the antidiarrhoeal activity of aegle marmelos. Bel, beli, belgiri hindi bilva, shivdhruma, shivaphala, vilva sanskrit marredy malyalam belo oriya vilva marum, vilvama tamil chemical composition aegle marmelos having variety of classes of compound like alkaloids, cardiac glycoside. The chemical composition of bael fruits is influenced by environmental factors. Phytochemistry and medicinal uses of the bael fruit aegle. Aegle marmelos linn correa, commonly known as bael or bel, belonging to the family rutaceae, is a moderatesized, slender and aromatic tree.
Post harvest management and value addition in bael aegle. Phytochemical and pharmacological screening of in vivo. Nadhiya and vadivazhagi antioxidant and phytochemical properties of combination international research journal of pharmaceutical and biosciences irjpbs 2015. Rutaceae is reported to be important plant in several ethnobotanical and ethnomedicinal studies for its antidiabetic, antiulcer, antiinflammatory, antipyretic, antioxidant and antimicrobial activity 44. Compounds 16 were isolated from the roots whereas compounds 79 were obtained from twigs. Corr indian journal of experimental biology, 47 2009, pp. It is found in india, burma, and sri lanka, often planted in the vicinity of shiva temples. The oil of twigs afforded the identifcation of 16 compounds, including eight monoterpene hydrocarbons 92. The chemical composition of bael is highly complex, containing many nutrients and other biologically active compounds, the proportions of which many vary considerably between strains and even among plants within the same field.
Aegle marmelos is a popular medicinal plant in the ayurvedic and. They form the easily available source for healthcare purposes in rural and tribal areas. Phytochemical analysis on leaf extract of aegle marmelos. Rapid simultaneous determination of marmelosin, umbelliferone. The chemical composition of fresh fruit in respect of water, carbohydrate, protein, fat, minerals, carotene, thiamine, riboflavin, niacin and. Experimental section the leaves of aegle marmelos were collected from, pechipparai region of south western ghats, agasthiyamalai. A novel herbal composition containing extracts of boswellia serrata gum resin and aegle marmelos fruit alleviates symptoms of asthma in a placebo controlled doubleblind clinical study. Various phytoconstituents have been isolated from the various parts of aegle marmelos, which. Post harvest management and value addition in bael aegle marmelos corr. Pdf phytochemistry and medicinal uses of the bael fruit. Introduction herbalism is a traditional medicinal or folk medicine. An hptlc chromatogram showing presence of marmelosin 7 in ripe fruit 1, unripe fruit 2, seed 3, leaves 4, rind 5, inner stem 6 and outer stem 8.
It is native to india and is also distributed in deciduous forest on hills and plains of bangladesh, burma and sri lanka. The potentially active chemical constituents present in the peppermint are menthol. Correa is an important fruit yielding and medicinal. Phytochemical analysis on leaf extract of aegle marmelos correa. Chemical composition of the leaf oil of aegle marmelos l. A number of chemical constituents and various therapeutic effects of leaves of aegle marmelos have been reported by different workers. Bael root is one of the ingredients of famous ayurvedic formulation dashmula. Seemaisamy r, faruck lh, gattu s, neelamegam r, bakshi ha, rashan l, albuloshi m, hasson ssaa and nagarajan k. Biological activities and volatile constituents of aegle. Because of this specific property the vilva is used in the treatment and preventive of all common ailment of mankind716.
Bael is native of northern india, but is found widely throughout the indian. The tree is used in several cooking preparations in india. In ayurveda, bael is utilized for its ability to treat an assortment of diseases, including diarrhea, dysentery, and. Department of chemistry, university of alabama in huntsville, huntsville, al 35899 usa. Aegle marmelos linn correa commonly known as bael or bel belonging to the family rutaceae, is a moderate sized, slender and aromatic tree.
Introduction diabetes mellitus is the one of the challenging health problem in twentyfirst century that is occurring throughout the world today. Chemical composition, phytochemical evaluation and development of functional product from bael aegle marmelos pulp powder. Bael is a slow growing, tough subtropical tree and is the only plant belonging to the. It is present in sri lanka, thailand, and malesia as a naturalized species. Sharma br, sharma p 1981 constituents of aegle marmelos ii. Aegle marmelos or bael is a middle sized slender aromatic armed tree native to india and pakistan.
Chemical constituents from the green fruits of aegle marmelos. Other names of bael include maredu, bill, bill patra, balwa, vilwam and kuvalam in india. Aqueous extract of aegle marmelos leaves, was evaluated for hypoglycemic and antioxidant effect 1, by using alloxon induced diabetes in male albino rats and proposed. Eagle marmelos had a potential to reduce chemical induced skin papillomas, reducing the tumour incidence, tumour yield, tumour burden, and cumulative number of papillomas.
Phytochemistry and medicinal uses of the bael fruit aegle marmelos correa. It is upto 15 m tall with short trunk, thick, soft, flaking bark and spreading spiny branches. A new natural product oxazoline derivative named aeglemarmelosine 1 along with eight known compounds 29 were isolated from roots and twigs of aegle marmelos. Phytochemistry and pharmacological properties of aegle marmelos. Bael or aegle marmelos is a spiritual, religious and medicinal plant, native of india and bangaladesh and spread throughout south east asia. Tremendous pharmacological values of aegle marmelos. Aegle marmelos, biological activity, chemical constituents. Tissue culture of endangered bael tree aegle marmelos. Correa, rutaceae, by capillary gc and gcms resulted in the identification of 35 components comprising 99. It grows wild all over the subhimalayan forests, central india and its west coast and in dry hilly places ascending to 4,000 ft. Chemical constituents present in differ ent parts of aegle marmelos sr.
A number of coumarins including xanthotoxol and alloimperatorin methyl ether, flavonoids including rutin and marmesin, alkaloids including alphafagarine, sterols and essential oils have been isolated from plant parts. Gas ion chromatogram of the essential oil of aegle marmelos l. They are a part of the basic research on the thai medicinal plants. Phytochemicals, nutritonal constituents, antibacterial and. Aegle marmelos has numerous components housed in various parts of the tree including. Aegle marmelos fruit pulp reported for the availability of steroids, terpenoids, flavonoids, phenolic.
All structures were characterized by extensive 1d and 2d nmr spectroscopic methods. Bael aegle marmelos or bilva is a medium sized deciduous sacred tree native to india and cultivated all over india. The major constituents of the root bark of the plant. Pdf chemical composition, phytochemical evaluation and.
The leaves of the plant have been reported to contain aegeline 1 and few alkaloids 24 of aegeline type manandhar et al. All structures were characterized by extensive 1d and 2d nmr. Aegle marmelos, alloxan, antidiabetic, hyperglycemia. Several research works have been done to identify active chemical constituents from various parts of bael plant. Physico chemical analysis of bael aegle marmelos fruit pulp. The dichloromethane dcm, ethyl acetate et0ac and nbutanol extracts of a. It is a medium sized deciduous tr ee belonging to family rutaceae. Evaluation of antioxidant potential and phytochemical. Proximate and phytochemical screening of the fruit and. Phytochemical and pharmacological screening of in vivo antiinflammatory activity of aegle marmelos l. It has a great mythological significance for hindus.
Aegle marmelos commonly known as bael is a plant indigenous to india. Correa has been widely used in indigenous systems of indian medicine due to its various medicinal properties. The other vernacular names are enlisted in table 1. However, despite its traditional usage as an antidiarrhoeal there is limited information regarding its mode of action in infectious forms of diarrhoea. Uses, side effects, interactions, dosage, and warning. Apart from these chemical constituents more than 100 compounds have been isolated these are skimminine, aegelin, lupeol, cineole, citral. Pdf chemical constituents from aegle marmelos researchgate. A number of chemical constituents and various therapeutic effects of leaves of a. Plant part chemical constituents 1 leaf skimmianine, aeglin, rutin. Chemical composition, antimicrobial and antifungal.
The plant, though, being highly explored, still lacks sufficient evidences for the best variety possessing the highest degree of medicinal values. The aegle marmelos contains more of natural antioxidant in the leaves and the fruit pulp. It is present in sri lanka, tamilnadu, thailand, and malesia as a naturalized species. Leaf powder crude against carbon tetrachlorideinduced hepatic damage in albino rats kuncha jayachandra1,thirunavukkarasu sivaraman2 1department of biochemistry, jaya college of pharmacy, chennai 602024, tamil nadu, india 2school of chemical and biotechnology, sastra university, thanjavur 6401, tamil nadu, india. Chemical composition, antimicrobial and antifungal activities of essential oils of the leaves of aegle marmelos l. Rutaceae, commonly known as bael, is used to treat fevers, abdomen pain. Phytochemical screening and estimation of total phenolic. Nadhiya and vadivazhagi antioxidant and phytochemical properties of combination. Google scholar tiwari bn, khatri p, ali j, soni ml, patel r. Biological activities and volatile constituents of aegle marmelos l. Supplementary data are available free of charge at, as pdf file. Surat l, chalita p, cholpisut t, somsak t, suphara ti, wanwasan n. Utilization of bael in daytoday life has great nutritional, environmental as well as commercial importance. Biological activities of crude extracts and chemical.
Some chemical constituents employed as markers for standardization of a. Aegle marmelos international research journal of pharmacy. Chemical composition, antimicrobial and antifungal activities. Anti microbial and anticancer activity of aegle marmelos and gas chromatography coupled spectrometry analysis of their chemical constituents. A derivative of benzoic acid, two alkaloids, five furanocoumarins, six coumarins, one dihydropyranocoumarin and six.
The chemical investigation of the leaves of this plant has revealed the presence of a number of alkaloids 27 and coumarins. Chemical constituents from aegle marmelos article pdf available in journal of the brazilian chemical society 221. Bael aegle marmelos has been known to be one of the most important medicinal plants of india since charak 1500 b. Phytochemical composition of aegle marmelos different organic extracts of the leaves of a. Minor constituents are like ascorbic acid, sitosterol, crude fibers, tannins. The present research work is aimed to summarize the ethnobotanical and pharmacological aspects of d. In colloquial terms they are known as bengal quince, indian quince, holy fruit, golden apple in english, and bael or bilva in hindi chemexcil, 1992, sharma et al. Aegle marmelos, antibacterial, anticancer, antidiabetic, antifungal, antihyperlipidaemic, antioxidant. The oil was constituted mainly of monoterpene compounds 93. Gas chromatography and mass spectroscopy analysis and. Hence, we evaluated the hot aqueous extract decoction of dried unripe fruit pulp of a. The therapeutic value of aegle marmelos correa rutaceae, commonly known as bael, has been recognized as a component of traditional medication for the treatment of various human ailments. Evaluation of antiobesity effect of aegle marmelos leaves.
Physico chemical analysis of bael aegle marmelos fruit. Cultivar kagazi recorded highest moisture content 66. Aegle marmelos plant the deciduous leaves originates singly orin 2s 3s are of 3 5 oval leaflets, 4 10 cm. The chemical composition of bael fruit was studied by ram and singh 2003. Bael aegle marmelos is one of the medicinal plants of india. Mishrabiological activities of crude extracts and chemical constituents of bael, aegle marmelos l. Aegle marmelos, rutaceae, phytochemical constituents, pharmacological activity. Wood apple is a sweet, aromatic and astringent in nature.
1158 919 624 1390 1156 1228 978 1391 539 61 53 1473 1221 1292 92 873 1059 203 1237 932 736 425 502 1295 52 1112 148 1063 1530 232 420 1498 871 1413 644 1082 389 447 1178 367 1022 1126 1444 499 573 136 123 134 1208